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Monica Bertagnolli, a 1985 graduate of the Spencer Fox Eccles School of Medicine at the University of Utah, was confirmed Tuesday by the U.S. Senate as the 16th Director of the National Institutes of Health (NIH) in Bethesda, Md. She is the first medical doctor trained in Utah to serve in this important national leadership role.
As NIH director, Bertagnolli will oversee the largest public funder of biomedical research in the world. The NIH has a budget of more than $47 billion and is comprised of 27 separate institutes and centers.
“We look forward to supporting Dr. Bertagnolli as she now leads the National Institutes of Health,” said Michael L. Good, CEO of University of Utah Health. “Her accomplished career serves as a beacon for our students, faculty and community at large.”
“It’s no surprise to many that an alum from the Spencer Fox Eccles School of Medicine has become the nation’s top scientific leader,” Good continued. “We’re proud that her medical education here helped set the trajectory for an incredible and accomplished career.”
A cancer surgeon, Bertagnolli became the first female director of the National Cancer Institute (NCI) in October 2022. She was also the first woman to lead the Dana-Farber Cancer Institute’s surgical oncology division in Boston. She will be the first surgeon to lead the NIH and its second female director, following in the footsteps of Bernadine Healy, who served as NIH director from 1991 to 1993.
“There has never been more potential for progress than what we have today. We just need to harness it. NIH can and must support research that is equitable and accessible to all populations. And this includes dramatically increasing clinical trials that reflect the full diversity of Americans because we know that’s what yields the best results,” Bertagnolli told the Senate at her Oct. 18 confirmation hearing. “And we must interrogate the broad range of behavioral and social science challenges we face today while laying the foundation to address new issues that will arise in the future.”
Prior to becoming director of the NCI, Bertagnolli served as chair of the U’s Huntsman Cancer Institute External Advisory Board. In that position, she played a key role in advising Huntsman Cancer Institute on strategy for its cancer research efforts and particularly the institute’s enhanced commitment to the Mountain West.
“Monica Bertagnolli’s invaluable contributions to Huntsman Cancer Institute were instrumental in shaping our strategic vision for cancer research and treatment in rural Utah, Idaho, Nevada, Montana and Wyoming,” said Mary Beckerle, the institute’s CEO. “Her dedication and insight have left an indelible mark on our mission, reflecting a commitment to advancing access to cancer care that resonates far and wide.”
Bertagnolli has been at the forefront of the field of clinical oncology throughout her career, according to the NCI. Her research focuses on the genetic mutations that lead to gastrointestinal cancer and how inflammation stimulates cancer growth.
The daughter of first-generation Italian and French Basque immigrants, Bertagnolli grew up on a 4,800-acre ranch nestled along the foothills of the Wind River Range in southwestern Wyoming. She received her undergraduate degree in engineering from Princeton University but soon found herself drawn to medicine.
“About halfway through college, I still loved engineering but did not want to work in an oil field or manufacturing,” Bertagnolli recalled in article published in a ASCO Post article in 2018. “I wanted to apply engineering to human biology, so the logical step was to go to medical school.”
A surgeon “on top of her game”
She applied to and chose the University of Utah medical school largely because of its immunology program. But a funny thing happened on the way to her medical degree: she fell in love with surgery.
“I signed up for surgery as my very first clinical rotation, just because I wanted to get it out of the way,” Bertagnolli told the ASCO Post. “I still vividly remember my first day in an operating room because I immediately knew that’s where I belonged.”
Dale Hull, a medical school classmate, remembers Bertagnolli as focused and driven.
“Monica was always on top of her game. very steady, unflappable, and extremely bright,” says Hull, co-founder and executive director of Neuroworx, a non-profit outpatient facility in Sandy that provides after-hospital rehabilitation for patients working to recover from spinal cord injuries. “I am not at all surprised to find her being selected for this type of responsibility. She is a focused hard worker who moves forward with grit.”
After Bertagnolli graduated from the U’s medical school, she trained in surgery at Brigham and Women’s Hospital and was a research fellow in tumor immunology at the Dana-Farber Cancer Institute.
Prior to her appointment as NCI director, Bertagnolli was a professor of surgery at Harvard Medical School and chief of the Division of Surgical Oncology at Brigham and Women’s Hospital and Dana-Farber Cancer Institute. She previously served as an associate surgeon at the Strang Cancer Prevention Institute in New York from 1994-2007 and as an attending surgeon at NewYork-Presbyterian/Weill Cornell Medical Center from 1994 to 1999.
Bertagnolli has been president of the American Society of Clinical Oncology, a professional organization for physicians and oncology professionals caring for people with cancer. She has also led the Alliance for Clinical Trials in Oncology, a network that works with the NCI to develop and conduct cancer clinical trials.
In December, Bertagnolli announced that she had been diagnosed with early-stage breast cancer. She told the Senate she has completed her treatments and her prognosis is excellent.
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Associate director, science communications, U of U Health